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Recently, we have further shown that FENNS patients have significantly lower 5-HT amplification than the normal control subjects (Reddy et al., 2007)

The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome

In addition to clinical trials, some TCMs, such as Rhodiola rosea , 393 Hippophae rhamnoides , 394 Aesculus chinensis , 395 Portulaca oleracea Linn ( Portulacaceae ), 396 Phlomis younghusbandii Mukerj ( Lamiaceae ), 397 Pueraria lobata , 398 Eleutheroside B , 399 and Notoginsenoside R1 , 400,401 showed promise in preventing HAPE/HACE in rat models by inhibiting the infiltration of inflammatory cells, the production of inflammatory cytokines, and apoptosis/pyroptosis

Glutathione has long been recognized as a central intracellular antioxidant, and ongoing clinical conversations continue to broaden how its role is understood across oxidative stress, inflammation, neurotransmission, and cellular resilience