bpc-157 recommended dosage benefits, dosage, and side effects The Complete BPC-157 Dosage Guide:

In rare cases where B12 is essential but acne remains intractable, dermatologists may consider oral isotretinoin, which in the UK can only be initiated by consultant dermatologists and requires strict monitoring, including a pregnancy prevention programme for women of childbearing potential

For more about why B-12 is important and how much you need (depending on age and gender), see the Vitamin B-12 section of the B Vitamin Supplements Review

Simultaneously it will deliver large conc

This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice