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As regulatory requirements become more stringent and consumer expectations for product quality and transparency continue to rise, the competitive advantage favoring larger, better-capitalized manufacturers is expected to intensify, potentially resulting in further consolidation within the industry

One hypothesis that can account for the observation of an increased risk for asthma attacks with LABA monotherapy is that patients may feel better when taking long-acting beta agonists, and as a result take either lower doses of inhaled corticosteroids, or no corticosteroids at all

Klein C, Westenberger A