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Acacetin binds specifically to the ATP domain of HSP90, causing HSP90 to detach from COX-2, which leads to COX-2 being ubiquitinated and broken down in macrophages, thereby reducing inflammatory reactions (189)

These latter supports help avoid column clogging due to solid contaminants by allowing the creation of a fluidized or expanded bed during sample application [42,50]

Graphical Abstract Similar content being viewed by others Introduction Gastric ulcer disease (GUD) is a common digestive tract disorder affecting around four million people per year worldwide (Abbasi-Kangevari et al