interaction of chloroacetamide electrophiles with cellular glutathion Selective covalent targeting GPX4 using masked nitrile-oxide Discovery of novel benzylaniline derivatives

Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Cellular Exposure to Chloroacetanilide Herbicides Induces Distinct Protein Destabilization Profiles ScienceDirect Delineating cysteine reactive compound modulation of cellular proteostasis processes Nature Chemical Biology Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv

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