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As an effect of ROS on the central nervous system (CNS), which has a high lipid content and high oxygen consumption, the oxidative agents promote lipid peroxidation, leading to membrane fluid loss, suppressing membrane potential, and increasing the accumulation of ions, particularly Ca 2+

Catalase Activity Analysis The activity of CAT was analysed based on the methods by the team of Aebi ( 2 O 2 (30 mM) was added to 2 ml of enzyme solution to initiate a reaction

With regard to how GPX1 influences the apoptotic outcome, the pieces of evidence indicate that GPX1 may influence several steps in apoptotic cascades via regulating oxidant accumulation

Li Q, Lan X, Han X, Durham F, Wan J, Weiland A, et al