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Description

Introduction Melanoma consists of various subtypes that vary based on the site of origin and pathogenesis

Long-term proliferation of human melanocytes is supported by the physiologic mitogens alpha-melanotropin, endothelin-1, and basic fibroblast growth factor

The next few images show naevi that appeared clinically atypical but had benign histology

[PUBMED Abstract] Dummer R, Ascierto PA, Gogas HJ, et al.: Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial