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1,7 The true prevalence is unknown because many women with polycystic ovary syndrome are undiagnosed, but it is believed that about 520% of women of reproductive age are affected

The underlying mechanism of this phenomenon remains unclear

Kidneys along with carotid bodies functions as the main hypoxia sensors which elicit reflex responses that include elevated sympathetic activity, vascular resistance and arterial blood pressure 4,5

Supplementing with oral glutathione under conditions in which intracellular glutathione status is compromised can restore tissue glutathione and promote ROS metabolism, thereby mitigating tissue atrophy, according to a 2017 study published in the World Journal of Gastroenterology.