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The effects of NTZ were compared to those of the standard antioxidant, N-acetyl cysteine (NAC), as a well-documented hepatoprotective agent known to inhibit ER stress, and to those of 4-phenyl butyrate (4-PBA), a standard ER stress inhibitor (Soliman et al., 2019)

NOX4 was shown to be involved in the development of hypertension in Dahl salt-sensitive (DSS) rats [70]

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Conversely, for individuals with HIV lipodystrophy treated with tesamorelin, GH and IGF-I levels are increased but insulin sensitivity remains preserved