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Microglia and astrocytes in the CNS are activated to release inflammatory factors and damage neurons, and in the peripheral immune system, alterations in blood immune cell subsets and function, and elevated inflammatory factors correlate with central inflammatory and neurodegenerative changes, but the consistency is influenced by clinical phenotype and disease stage [160, 161]

The integrity of the BBB suffers a certain degree of damage post-IS, and this change permits the drug to enter the brain parenchyma through passive diffusion mechanisms

It is not suitable for individuals with shellfish allergies

Antitoxin actions describe a nutrient or bioactive that helps neutralize and bind with toxins and cellular debris to support their clearance from the body