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The signs and symptoms of anemia are as follows: Dyspnea, shortness of breath, difficulty breathing, inability to take deep breaths

Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects

Cell-based experiments confirmed that puerarin promoted the protein expression of SLC7A11 and regulated SLC7A11-mediated glutathione content and reactive oxygen species (ROS) levels

Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency