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In regard to aging and cellular metabolism, the shortening of telomeres (TLs), complexes of deoxyribonucleic acid (DNA), can lead to the increased risk for the development of DM (267) and greater cell senescence with the loss metabolic homeostasis (178, 190, 268)

As the DMSO concentration increased, there was also an increase in reduced glutathione and a progressive increase in membrane anisotropy (an inverse measure of membrane fluidity), explained as a reaction compensating for the pro-oxidant effects of DMSO on components of cytosol and cell membranes 27

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The pia mater: a comprehensive review of literature