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2012) and post-mortem brains (Chauhan et al

The VEGF monoclonal antibody, ranibizumab, significantly improved synovial inflammation in CIA rats and was superior to the IL-6 monoclonal antibody, tocilizumab, in terms of anti-bone destruction (271)

The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells