tobacco center of regulatory science TCORS — REBEL Research CAsToR Symposium 2023: “The use

Moderate drinking: Up to one drink per day for women, two for menthough no level is universally safe Binge drinking: Four or more drinks in about 2 hours for women, five or more drinks for men, bringing BAC to ~0.08 Heavy drinking: 8+ drinks weekly for women, 15+ for men Age, sex, medications, liver health, and genetics all influence when too much alcohol becomes dangerous For those with liver disease, addiction history, heart conditions, or pregnancyabstinence is safest Needing more alcohol to feel the same effect signals developing alcohol dependence Long-Term Effects on the Brain and Mental Health Repeated heavy drinking changes the brains chemistry, making alcohol feel necessary for normal function

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Nicotine is more addictive physiologically in our brain than even cocaine or heroin is, said Russell Buhr, MD, PhD, a pulmonologist at UCLA Health who also runs an outpatient practice in Westwood