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Mechanistically, this analgesic effect has been correlated to cGMP-dependent enhanced release of gamma-aminobutyric acid (GABA) [144]

Thompson, M

GSH is briefly overviewed hereunder before discussing other SH compounds and S-donor ligandsPCs and MTs in detail

The topical formulations of such substances may thus offer a unique alternative to avoid their binding to CB1 receptors at the central level by employing the structures of the epidermis as a reservoir for cannabinoids