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Sermorelin is often considered a gentler alternative to CJC-1295 with ipamorelin, with a shorter duration of action that more closely mimics natural GHRH release patterns

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Consistent with the observation that mitochondrial diseases preferentially affect tissues with greater energy demands, disruptions in mitochondrial function have been suggested to have a role in the development of POAG (Beidoe and Mousa, 2012