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Ciliary beat frequency: proceedings and recommendations from a multi-laboratory ring trial using 3-D reconstituted human airway epithelium to model mucociliary clearance

Here, we report that excessive amounts of FA decrease arborization of deep layer projection neurons, but not upper layer neurons and that reduced complexity of deep layer neurons is not observed when folic acid is replaced by folinic acid, a stable reduced form of folate

Mechanistically, DJ-1 prevents the enhanced inhibitory interaction between SAHH and its negative regulator S-adenosylhomocysteine hydrolase-like 1 protein (AHCYL1), thereby promoting the formation of catalytically active SAHH tetramers