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At steady state, however, cellular IL-1 expression is often undetectable and the ligation of pattern recognition receptors (PRR), such as Toll-like receptors (TLRs), is required to induce transcription of inactive pro-IL-1

Rapid structure determination by copper SAD phasing could be achieved, even at a very low Bijvoet ratio or after significant radiation damage

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Moreover, HBM only provides a snapshot of the biological status of the participant, missing between and within day variability, which is crucial for short half-life mycotoxins