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As a result, tears occur around the blood vessels, causing the thick fluid to potentially leak out and accumulate on one side

, 2004, vol

10.1254/jphs.08r26fm 124 OkumuraS.TakagiG.KawabeJ.-i.YangG.LeeM.-C.HongC.et al (2003b)

These modifications not only hinder their microcirculatory movement but also function as molecular signals that facilitate their identification and removal by the reticuloendothelial system