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129 Among the various inflammatory cytokines produced by innate immune cells in response to SARS-CoV-2 infection, it has been identified that the co-production of TNF and IFN- uniquely triggers PANoptosis

In NAFLD, hepatic uptake and de novo lipogenesis are increased, while a compensatory enhancement of fatty acid oxidation is insufficient in normalizing lipid levels and may even promote cellular damage and disease progression by inducing oxidative stress, especially with compromised mitochondrial function and increased oxidation in peroxisomes and cytochromes

In contrast, no such association was observed in males

Pengel LH, Barcena L, Morris PJ