glutathione shuttle The Science and Translation of Lactate Theory: Cell Metabolism Glutathione Synthase - an overview

The resulting mitochondrial disruption not only triggers apoptosis but also stimulates innate immune pathways, including the NLRP3 inflammasome and the cGASSTING axis, amplifying local inflammation and enhancing immune surveillance [282]

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There is also the issue of the trees

Acknowledgements We would like to thank the participants enrolled in the study and acknowledge Yihao Chen and Wu Nv for their kind assistance in participant recruitment, sample, and clinical data collection