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The reductionist model has stagnated pharmacological research, which has not produced any substantial innovation for approximately half a century, particularly for the treatment of depression, the level of effectiveness of which is modest [17] and antidepressant drug mechanisms shrouded in fog [10]

Despite the enhanced GPx activity, GSSG concentration of pathogen-inoculated susceptible genotypes at 7 DPI remained significantly lower mainly due to enhanced GR activity, which rapidly converts GSSG in to GSH