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For cretinism in iodine-deficient areas, Se supplementation should not be promoted prior to iodine supplementation or when there is no plan for iodine supplementation, as stated by the American Thyroid Association, The differential intakes of iodine, Se, or both in different regions must be considered before any action for Se supplementation is taken (69)

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Por tanto, los niveles totales no siempre reflejan el estado funcional de la tiroides, especialmente en situaciones como el embarazo o el uso de anticonceptivos, donde puede aumentar la TBG y disminuir la fraccin libre

The HDL proteome has been extensively studied and there is a general consensus of approximately 80 proteins (770,771)