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Primary research: Mitochondrial dysfunction, Barth syndrome, heart failure, age-related mitochondrial decline Mechanism: Binds cardiolipin in the inner mitochondrial membrane, stabilizing electron transport chain function and reducing reactive oxygen species Regulatory status: FDA-approved (Forzinity) for Barth syndrome

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The network diagram between riboflavin, osteogenesis and significantly enriched KEGG pathways was further plotted and presented in Fig

Results: Our study included 1829 patients with a median (interquartile range) follow up of 8.20 (3.40-15.80) years