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Vitamin B12 is required for the catabolism of fats and proteins, processes pertinent to weight management

The 2018 paper in Biochemical Pharmacology gave obese mice a membrane-permeable NNMT inhibitor and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with the mice eating the same amount as before, and the authors noting the inhibitors did not impact total food intake nor produce any observable adverse effects [1]

N-acetylcysteine in the treatment of excoriation disorder: a randomized clinical trial

Long COVID, studied widely in recent years, also shares common features with these conditions, and this further complicates the landscape, as studies indicate that 2031% of Long COVID patients also meet FM diagnostic criteria 6 months post-infection (Fernndez-de-Las-Peas et al., 2022