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Description

Next, we used a targeted LC-MS metabolomics assay to confirm these trends in one additional sensitive cell line (U87) and one additional resistant cell line (A172)

Deletion analysis of Hdc promoter-driven luciferase reporter gene transcription demonstrated that the transcription factor SP1 binds to a GC box (GGGGCGGGG) found in both the human and mouse Hdc gene promoters (72, 74)

& Gage, F

This new scientific study hails the multitargeted functions of carnosine , and suggests new mechanisms by which carnosine may prevent glycation - and oxidative stress-related cataract formation