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Pathophysiological Mechanisms and Etiology of CLBP Intervertebral disc degeneration is frequently implicated in discogenic pain, as degenerative disc disease leads to loss of disc height, annular fissures, reduced shock absorption, and internal disc disruption that may provoke nociceptive signaling from the annulus fibrosus [6,7]

SIFO , small intestine fungal overgrowth, can be screened for using an Organic Acids urine test, symptom history and clinical correlation

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Pyruvate is a key intermediate in the bodys metabolism, particularly in the process of converting carbohydrates into energy