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Interestingly, the foregoing experimental in vitro evidences were confirmed by in vivo studies with microdialysis probes implanted in the frontal cortex of adult Wistar rats (Juarez et al., 2002), showing increased levels of extracellular glutamate after MeHg exposure

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This selectivity profile has made it a subject of interest for researchers seeking to stimulate GH release with a narrower endocrine perturbation profile