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The quality of the evidence was extrapolated from the risk of bias and was described by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) terminology as very low, low, or high, and, for meta-analyses, it was described by the GRADEpro Guideline Development Tool (GDT

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In a patient with fatal VHT, Krahenbuhl and coworkers [57] demonstrated a reduction in free and total carnitine in plasma and liver

In certain cases, it can even help protect the brain from cell damage