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The Use of Computational Approaches to Design Nanodelivery Systems

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Downstream, GPx mimetics and the endogenous peroxiredoxin/thioredoxin (Prx/Trx) cycle clear residual H 2 O 2 with high efficiency while maintaining the redox tuning needed for physiologyallowing reversible cysteine oxidations that encode normal signaling, yet preventing the sustained or widespread oxidation that tips cells into dysfunction