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In addition to haemodynamic overload, uraemic toxin accumulation and altered ion homeostasis, which are known to underlie left ventricular hypertrophy in CKD and drive cardiac dysfunction, we examine the role of myocardial metabolic remodelling in CKD

It is also worth investigating whether betaine deficiency is associated with the pathogenesis or with the severity of the above diseases

2 La L-carnitine possde plusieurs groupes fonctionnels et peut tre utilise comme matire premire pour la synthse organique

Long-chain FAOD (LC-FAOD) should be considered in any patient with cardiomyopathy, especially a new and acute onset