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Patients with CS have increased morbidity risks for various malignant tumors, particularly breast, thyroid, and endometrial cancers

The establishment of standardized protocols for biomarker assessment in clinical settings remains an ongoing challenge

Further investigations have identified two broad categories of organ failure in AP: early primary organ failure, which occurs within 72 h due to systemic inflammation, and late secondary organ failure, which typically develops after one week and is often linked to infectious pancreatic necrosis

T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays