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However, given our previous findings implicating the glutamine-glutamate ratio in effortful performance 28 , and recent evidence indicating that GSH may be a physiological reservoir of glutamate neurotransmitter when the glutamate-glutamine shuttle is inhibited 59 , the alternative non-mutually exclusive possibility that higher GSH levels may be contributing to the glutamate-glutamine cycle [or vice versa

For details, see the B6 section of the B Vitamin Supplements Review

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