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While Vitamin B12 supports metabolism and energy, it is most effective when combined with healthy eating and exercise

In addition, efflux transporters such as P -glycoprotein ( P -gp) and breast cancer resistance protein (BCRP) actively remove many therapeutic agents from the brain (Kadry et al., 2020)

Getting enough vitamin B12 is absolutely non-negotiable for those centering their diets around plant-based foods