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This article is the first in a four-part series that reviews recent literature on cutaneous adverse reactions experienced with commonly prescribed biologic and targeted therapies, specifically tumor necrosis factor (TNF) alpha inhibitors, epidermal growth factor receptor (EGFR) inhibitors, small-molecule tyrosine kinase inhibitors (TKIs), and frequently used cell surface-targeted monoclonal antibodies

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They improve insulin sensitivity, reduce appetite, slow gastric emptying, and promote significant fat loss while preserving lean muscle mass when combined with proper nutrition and resistance training