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After controlling for sex, age, and BMI z-score, PNPLA3 GG carriers were nearly 20 times more likely to have HS than CC (Odds Ratio [OR] 19.93, p=0.003) and CG carriers nearly 6 times more likely than CC carriers (OR 5.61, p=0.069)

The transcription factors ATF4 and Nrf2 couple ER stress to a general cellular response that increases the production of glutathione by increasing aminoacid metabolism (Cullinan et al , 2003

In a parturition-induced SUI rat model, an oligo microarray analysis revealed increased expression of genes involved in inflammation (Smad2/TGF-B), smooth muscle regulation (RGS2), and collagen metabolism (MMP13) (Lin et al

Glutathione Glutathione is an essential molecule that acts as a powerful antioxidant and its involved in different bodily functions like the immune system and tissue repair