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Description

Potential role of integrin 5 1 /focal adhesion kinase (FAK) and actin cytoskeleton in the mechanotransduction and response of human gingival fibroblasts cultured on a 3-dimension lactide-co-glycolide (3D PLGA) scaffold

Because essentially identical structures were determined using our MBP-mediated crystallization strategy, and we observed minimal interactions between the MBP tag and the targets in our current studies, our data suggest that fusion protein tags such as MBP are unlikely to interfere with the structure or folding of death domains, and maybe other protein targets as reported previously 1,37