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Furthermore, a recent study demonstrated that oxaliplatin inhibited prolyl hydroxylase, an enzyme that hydroxylates proline in the N-terminal ankyrin repeat of TRPA1, which leads to the enhanced sensitivity of TRPA1 (Miyake et al., 2016)

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Causal effects of gut microbiome on systemic lupus erythematosus: A two-sample mendelian randomization study

Retinopathy and nephropathy are later events that are actually due to microangiopathy, excessive budding and growth of new blood vessels and capillaries, which often will bleed due to weakness of the new vessel walls