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Chen et al (56) reported that, after phototherapy, the expression of Bmal1 decreased in peripheral monocytes of neonates, whereas the expression of Cry1 was significantly enhanced, whereas the plasma melatonin, which is involved in the regulation of the circadian rhythm (57,58), was downregulated

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All mice were enrolled in the study in numerical order and randomly allocated to experimental groups by lottery, with the group allocation performed by a third-party investigator to ensure that the experimenters remained blinded to group assignments

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