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studied the ROS content in neutrophils of different age groups and found that the intracellular ROS content increased significantly in people aged 6089 years compared with those aged 2059 years

By interacting directly with MAPKs, including c-Jun N-terminal kinase 1 (JNK1) and apoptosis signal-regulating kinase 1 (ASK1), GSTs bind the ligand in a complex structure, preventing interactions with their downstream targets [74]

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