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85 , 95 , 96 , 121 Children with autism show significantly elevated oxidative stress, as indicated by the increased GSSG/GSH ratio (glutathione is the primary antioxidant in the body) and increased plasma nitrotyrosine

Galozzi P, Oliviero F, Frallonardo P et al (2016) The prevalence of monosodium urate and calcium pyrophosphate crystals in synovial fluid from wrist and finger joints

For example, mitochondrial ferritin reduces iron content by storing iron, GPX4 and dihydroorotate dehydrogenase (DHODH) in the mitochondria eliminate lipid peroxides (Mao et al., 2021), and CDGSH iron sulfur domain 1 (CISD1) and voltage-dependent anion channel (VDAC) regulate iron concentration and respiratory substrate content in mitochondria, respectively (Lemasters, 2017

Prolonged serious deficiency of iodine causes a greatly enlarged thyroid gland called goitre or crop