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The study showing copper peptides increased collagen in 70% of users versus 40% for retinoic acid suggests copper peptides may actually be more effective for collagen building specifically, though retinoids offer additional benefits (texture improvement, dark spot reduction) that copper peptides don't provide as strongly

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Nutrients 10 (11), 1651

Healthcare providers should maintain heightened clinical suspicion for malignancy in patients receiving these peptides and should promptly investigate any concerning clinical findings