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These include alcohol consumption, smoking, foods that act as stimulants, foods high in acid such as certain fruits (e.g., pineapples, oranges), foods rich in potassium, caffeinated beverages like tea and coffee, and various other dietary elements (zhong et al., 2010

Furthermore, through the TRXTXNIP axis, Nrf2 activation indirectly inhibits NLRP3 activation by promoting the production of antioxidant enzymes that preserve TRX in a reduced state [90]

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