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Comparing Effectiveness Across Administration Routes Choosing the best way to get B12 depends on several things

Vitamin B12 shots may not be suitable for people with a history of: sensitivity to vitamin B12 Lebers disease, which affects the optic nerve kidney problems hypokalemia (low potassium levels) deficiencies in other nutrients, particularly folic acid and iron Vitamin B12 injections typically begin to work straight away

have an irregular or fast heartbeat (arrhythmia) What not to do after a B12 injection

Since the dosage is given in units per kg of weight, you will first have to multiply your weight by the dosage: 5 mcg/kg 78 kg = 390 mcg To understand how this microgram dose translates into an actual injection volume based on concentration, you can convert mcg to mL using the solution's concentration