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Hypothesis 2: Inflammation, Alcohol and the Lymphatic System Further research is needed to determine the exact pathophysiology involved in the development of MSL fat tissue, but the fact that alcohol is damaging to many tissues in the body suggests that inflammation may play a role

TMEM175 deficiency impairs lysosomal and mitochondrial function and increases -synuclein aggregation

The activation of CDKN1A/p21-mediated GSH metabolism by p53 can inhibit cellular ferroptosis (Fig

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