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Ferroptosis has been implicated in the occurrence and treatment response of various types of cancer, and targeting ferroptosis has emerged as a promising strategy for cancer therapy

However, excessive/insufficient mitophagy, inhibition of mitochondrial biogenesis, and an overall reduction in protein synthesis can lead to mitochondrial dysfunction, causing insufficient ATP production or an increased burden of ROS, which in turn cannot meet the cellular demands, ultimately leading to energy deprivation and cell death

The clinical significance of our findings supports the use of amlodipine as an adjuvant therapy in patients with IOC

Do not contain Disodium EDTA or any type of Chelating Agent in the formula because Disodium EDTA will bind to the copper ions and make Copper Peptide, which is a component of Long-Lash, less effective