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Description

This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death

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doi: 10.1038/nrendo.2014.171 133

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However, when the reoxygenation was extended for longer, cell repair started and ECD decreased [136]

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FIGURE 2 TABLE 1 Regulation of p53 in ferroptosis network

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