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Trends Genet 29(9):513520

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CYLD: a tumor suppressor deubiquitinase regulating NF-B activation and diverse biological processes

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Mechanistically these three peptides complement each other : BPC-157 = the vascular component (angiogenesis, fibroblast migration) TB-500 = cellular material (mobilization of stem cells, actin) GHK-Cu = building material (collagen, glycosaminoglycans, ECM remodeling) In the community this triple combination is sometimes called the regeneration orchestra , each peptide plays a different role in the complex symphony of healing

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