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(US Patent 8598118) characterized hepatocyte growth factor mimics as therapeutic agents and established the mechanistic basis for Dihexas development

In TNBS- and DSS-induced models of colitis, activation of CB2 receptor has been shown to contribute to the reduction of inflammatory cell influx, cytokine and chemokine secretion, and to improve macroscopic and histological inflammatory changes in the collected material

Additional treatment approaches being vigorously pursued include monoclonal antibodies designed to attenuate and block the production and deposition of insoluble amyloid (A) protein fragments resulting from amyloid precursor protein proteolysis

Cagrilintide is a long-acting analog of amylin a pancreatic satiety hormone acting on the amylin receptor