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doi: 10.1016/j.clim.2014.02.016 46 HorckmansMRingLDucheneJSantovitoDSchlossMJDrechslerMet al

This suggests LL-37 acts as an alarm system, redirecting mast cells from allergic mode to infection-fighting mode when bacteria are present

Future investigations must elucidate the molecular mechanisms underlying NMDR patterns, particularly focusing on hormone receptor binding kinetics, metabolic clearance rates, and compensatory cellular responses that may explain these complex relationships